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Treatment of irritable bladder dysfunction and urinary frequency caused by benign prostatic hyperplasia (BPH) and urinary tract inflammation…

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Indications

Irritable bladder dysfunction and frequent urination caused by benign prostatic hyperplasia (BPH) and inflammation of the urinary tract. Pumpkin has traditionally been used internally as a...
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Direction for use

Take one capsule, 3 times a day, with a glass of water.

Product description

This hard gel is composed of pumpkin oil, obtained by cold press of Cucurbita pepo L. seeds and content of vitamin E.
:Constituents
Pumpkin oil is a source of fatty acids include linoleic, oleic, palmitic and stearic acids, vitamin E, phytosterols, tocopherols (α,β,γ), carotenoids (lutein & β-carotene) and cucurbitine

Use cases

Irritable bladder dysfunction and frequent urination caused by benign prostatic hyperplasia (BPH) and inflammation of the urinary tract. Pumpkin has traditionally been used internally as a laxative to treat constipation, and as a demulcent for cough.

Instructions for use

Take one capsule, 3 times a day, with a glass of water.

side effects

No adverse effects have been reported.
Contraindications & Precautions
Information regarding safety and efficacy in pregnancy and lactation is lacking. Avoid use.
Taking more than the recommended dose should be avoided.

Mechanism of action

Experimental model have been suggested to be due to phytosterols of pumpkin seed oil (PSO), are known to inhibit 5 α-reductase and to have antiandrogenic effects. Delta-7-sterols, is stopped agents of Dihydrotestosterone (DHT) androgen receptors and thus it is inhibits the proliferation of prostate cells. Lower risk of prostate cancer is cause of dietary sterols. The effects of alpha-tocopherol and selenium are significant in preventing of oxidative damage to lipids, vitamins, hormones and enzymes. In experiments, a hypotensive action was demonstrated by the oil alone, and in combination with captopril and felodipine, also some constituent isolated from pumpkin seeds act as trypsin- inhibitors. The anthelmintic effect is attributed to the constituent cucurbitine. The efficacy of Pumpkin seed oil (PSO) for benign prostatic hyperplasia (BPH) and Urodynamic effects, Cardiovascular activity, Anti-inflammatory activity, Hypolipidemic effects, Antioxidant activity, etc. confirmed by numerous experimental studies (Clinical and animal models).

Interferences

Concurrent use with warfarin may increase INR.
In concurrent use of anticoagulants drugs such as warfarin and clopidogrel should be controlled PTT and coagulation factors.

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